Package: grantham 0.1.1
grantham: Calculate the 'Grantham' Distance
A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
Authors:
grantham_0.1.1.tar.gz
grantham_0.1.1.zip(r-4.7)grantham_0.1.1.zip(r-4.6)grantham_0.1.1.zip(r-4.5)
grantham_0.1.1.tgz(r-4.6-any)grantham_0.1.1.tgz(r-4.5-any)
grantham_0.1.1.tar.gz(r-4.7-any)grantham_0.1.1.tar.gz(r-4.6-any)
grantham_0.1.1.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
card.svg |card.png
grantham/json (API)
NEWS
| # Install 'grantham' in R: |
| install.packages('grantham', repos = c('https://ramiromagno.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/maialab/grantham/issues
Pkgdown/docs site:https://maialab.org
- amino_acids_properties - Amino acid side chain property values
- grantham_distances_matrix - Grantham distance matrix
Last updated from:6768b1f580. Checks:9 OK. Indexed: no.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| linux-devel-x86_64 | OK | 124 | ||
| source / vignettes | OK | 173 | ||
| linux-release-x86_64 | OK | 114 | ||
| macos-release-arm64 | OK | 79 | ||
| macos-oldrel-arm64 | OK | 83 | ||
| windows-devel | OK | 78 | ||
| windows-release | OK | 73 | ||
| windows-oldrel | OK | 70 | ||
| wasm-release | OK | 104 |
Exports:%>%amino_acid_pairsamino_acidsas_one_letteras_three_lettergrantham_distancegrantham_distance_exactgrantham_distance_originalgrantham_equation
Dependencies:clicpp11dplyrgenericsgluelifecyclemagrittrpillarpkgconfigpurrrR6rlangstringistringrtibbletidyrtidyselectutf8vctrswithr
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Generate amino acid pairs | amino_acid_pairs |
| The 20 standard amino acids | amino_acids |
| Amino acid side chain property values | amino_acids_properties |
| Convert three-letter amino acid codes to one-letter codes | as_one_letter |
| Convert one-letter amino acid codes to three-letter codes | as_three_letter |
| Grantham distance | grantham_distance |
| Grantham distance matrix | grantham_distances_matrix |
| Grantham distance | grantham_equation |
