Package: grantham 0.1.1

grantham: Calculate the 'Grantham' Distance

A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

Authors:Ramiro Magno [aut, cre], Isabel Duarte [aut], Ana-Teresa Maia [aut], CINTESIS [cph, fnd]

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grantham.pdf |grantham.html✨
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Bug tracker:https://github.com/maialab/grantham/issues

On CRAN:

9 exports 4 stars 1.00 score 21 dependencies 1 dependents 7 scripts 366 downloads

Last updated 1 months agofrom:6768b1f580. Checks:OK: 7. Indexed: no.

Exports:%>%amino_acid_pairsamino_acidsas_one_letteras_three_lettergrantham_distancegrantham_distance_exactgrantham_distance_originalgrantham_equation

Dependencies:clicpp11dplyrfansigenericsgluelifecyclemagrittrpillarpkgconfigpurrrR6rlangstringistringrtibbletidyrtidyselectutf8vctrswithr