gwasrapidd - 'REST' 'API' Client for the 'NHGRI'-'EBI' 'GWAS' Catalog

'GWAS' R 'API' Data Download. This package provides easy access to the 'NHGRI'-'EBI' 'GWAS' Catalog data by accessing the 'REST' 'API' <https://www.ebi.ac.uk/gwas/rest/docs/api/>.

Last updated 8 months ago

association-studiesgwas-cataloghumanrest-clientsnptraittrait-ontology

86 stars 4.14 score 58 dependencies 2 dependents

wig - Import WIG Data into R in Long Format

Import WIG data into R in long format.

Last updated 2 years ago

1.91 score 18 dependencies

quincunx - REST API Client for the 'PGS' Catalog

Programmatic access to the 'PGS' Catalog. This package provides easy access to 'PGS' Catalog data by accessing the REST API <https://www.pgscatalog.org/rest/>.

Last updated 2 years ago

ebigwaspolygenic-risk-scorespolygenic-scores

13 stars 1.38 score 48 dependencies

grantham - Calculate the 'Grantham' Distance

A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

Last updated 2 years ago

4 stars 1.33 score 21 dependencies 1 dependents

grantham - Calculate the 'Grantham' Distance

A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

Last updated 2 years ago

4 stars 1.32 score 21 dependencies 1 dependents

mskcc.oncotree - Interface to the 'OncoTree' API

Programmatic access to 'OncoTree' API <http://oncotree.mskcc.org/>. Get access to tumor main types, identifiers and utility routines to map across to other tumor classification systems.

Last updated 2 years ago

6 stars 1.18 score 43 dependencies

agvgd - An R Implementation of the 'Align-GVGD' Method

'Align-GVGD' ('A-GVGD') is a method to predict the impact of 'missense' substitutions based on the properties of amino acid side chains and protein multiple sequence alignments <doi:10.1136/jmg.2005.033878>. 'A-GVGD' is an extension of the original 'Grantham' distance to multiple sequence alignments. This package provides an alternative R implementation to the web version found on <http://agvgd.hci.utah.edu/>.

Last updated 7 months ago

2 stars 1.02 score 33 dependencies

agvgd - An R Implementation of the 'Align-GVGD' Method

'Align-GVGD' ('A-GVGD') is a method to predict the impact of 'missense' substitutions based on the properties of amino acid side chains and protein multiple sequence alignments <doi:10.1136/jmg.2005.033878>. 'A-GVGD' is an extension of the original 'Grantham' distance to multiple sequence alignments. This package provides an alternative R implementation to the web version found on <http://agvgd.hci.utah.edu/>.

Last updated 7 months ago

2 stars 1.02 score 33 dependencies

hospitals - Portuguese 'NHS' Hospitals

A data set of the Portuguese 'NHS' hospitals.

Last updated 3 years ago

0.62 score 13 dependencies

protean - Sequence Profiles of OncoKB Genes

A data package of sequence profiles of OncoKB genes. These profiles are obtained via Ensembl's REST API and derived from the pairwise alignment of the human sequence with its orthologs.

Last updated 8 months ago

0.23 score 43 dependencies

ensemblr - R Client for the Ensembl REST API

R Client for the Ensembl REST API.

Last updated 3 years ago

1 stars 0.09 score 40 dependencies

geisha - GEISHA Expression Data

GEISHA expression data. These data are obtained from GEISHA <http://geisha.arizona.edu/geisha/downloads.jsp/>.

Last updated 3 years ago

1 stars 0.09 score 36 dependencies