gwasrapidd - 'REST' 'API' Client for the 'NHGRI'-'EBI' 'GWAS' Catalog

'GWAS' R 'API' Data Download. This package provides easy access to the 'NHGRI'-'EBI' 'GWAS' Catalog data by accessing the 'REST' 'API' <https://www.ebi.ac.uk/gwas/rest/docs/api/>.

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thirdpartyclientbiomedicalinformaticsgenomewideassociationsnpassociation-studiesgwas-cataloghumanrest-clienttraittrait-ontology

8.35 score 102 stars 1 dependents 82 scripts 904 downloads

dtlg - A Performance-Focused Package for Clinical Trial Tables

Create high-performance clinical reporting tables (TLGs) from ADaM-like inputs. The package provides a consistent, programmatic API to generate common tables such as demographics, adverse event incidence, and laboratory summaries, using 'data.table' for fast aggregation over large populations. Functions support flexible target-variable selection, stratification by treatment, and customizable summary statistics, and return tidy, machine-readable results ready to render with downstream table/formatting packages in analysis pipelines.

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4.24 score 1 stars 6 scripts 500 downloads

wig - Import WIG Data into R in Long Format

Import WIG data into R in long format.

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3.48 score 8 scripts 186 downloads

agvgd - An R Implementation of the 'Align-GVGD' Method

'Align-GVGD' ('A-GVGD') is a method to predict the impact of 'missense' substitutions based on the properties of amino acid side chains and protein multiple sequence alignments <doi:10.1136/jmg.2005.033878>. 'A-GVGD' is an extension of the original 'Grantham' distance to multiple sequence alignments. This package provides an alternative R implementation to the web version found on <http://agvgd.hci.utah.edu/>.

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3.18 score 3 stars 6 scripts 272 downloads

agvgd - An R Implementation of the 'Align-GVGD' Method

'Align-GVGD' ('A-GVGD') is a method to predict the impact of 'missense' substitutions based on the properties of amino acid side chains and protein multiple sequence alignments <doi:10.1136/jmg.2005.033878>. 'A-GVGD' is an extension of the original 'Grantham' distance to multiple sequence alignments. This package provides an alternative R implementation to the web version found on <http://agvgd.hci.utah.edu/>.

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3.18 score 3 stars 6 scripts 233 downloads

hospitals - Portuguese 'NHS' Hospitals

A data set of the Portuguese 'NHS' hospitals.

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2.70 score 1 stars 2 scripts 205 downloads

grantham - Calculate the 'Grantham' Distance

A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

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2.65 score 3 stars 1 dependents 9 scripts 649 downloads

grantham - Calculate the 'Grantham' Distance

A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

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2.65 score 3 stars 1 dependents 7 scripts 631 downloads

dtlg.data - Benchmark Data for the 'dtlg' Package

A set of datasets to support benchmarking with the package dtlg.

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2.00 score 3 scripts

protean - Sequence Profiles of OncoKB Genes

A data package of sequence profiles of OncoKB genes. These profiles are obtained via Ensembl's REST API and derived from the pairwise alignment of the human sequence with its orthologs.

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1.70 score 4 scripts

geisha - GEISHA Expression Data

GEISHA expression data. These data are obtained from GEISHA <http://geisha.arizona.edu/geisha/downloads.jsp/>.

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1.70 score 1 stars